Detection of diffuse axonal injury in forensic pathology

نویسندگان

  • Sorin Hostiuc
  • Daniel Pirici
  • Ionut Negoi
  • Daniela Adriana Ion
  • Mihai Ceausu
چکیده

Even if βAPP remains the gold standard in identifying diffuse axonal injuries, other histological, ultrastructure, histochemical, or immunohistochemical markers may aid the diagnosis and may better characterize this traumatic brain pathology. Moreover, associated changes, including neuronal body changes, the presence of microglial clusters, and so on, when identified in a traumatic context, should suggest at least the need of using specific markers for identification of DAIs. The purpose of this article is to present the main microscopy techniques used in forensic practice to detect diffuse axonal injury.

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تاریخ انتشار 2014